Bariatric Surgery Improves Serum CD40L Levels as a Predictor of Cardiovascular Risk: Systematic Review and Meta-analysis.
In: Obesity Surgery, Jg. 34 (2024-05-01), Heft 5, S. 1929-1937
Online
academicJournal
Zugriff:
CD40 and its ligand have been recently implicated in the pathogenesis of cardiovascular disease (CVD). This meta-analysis examined the effect of bariatric surgery in reducing circulating CD40L levels. A systematic review was performed using Embase, Google Scholar, PubMed, Scopus, and Web of Science. The meta-analysis was provided by Comprehensive Meta-Analysis (CMA) V4 software. The overall effect size was detected by a random-effects meta-analysis and the leave-one-out approach. Random-effects meta-analysis of 7 studies including 191 subjects showed a significant reduction in CD40L after bariatric surgery (standardized mean difference (SMD), − 0.531; 95% CI, − 0.981, − 0.082; p = 0.021; I 2 , 87.00). Circulating levels of CD40L are decreased after bariatric surgery which may represent a mechanism for improvement of metabolic profile. [ABSTRACT FROM AUTHOR]
Copyright of Obesity Surgery is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Titel: |
Bariatric Surgery Improves Serum CD40L Levels as a Predictor of Cardiovascular Risk: Systematic Review and Meta-analysis.
|
---|---|
Autor/in / Beteiligte Person: | Jamialahamdi, Tannaz ; Eid, Ali H. ; Nguyen, Ninh T. ; Gadde, Kishore M. ; Sukhorukov, Vasily N. ; Almahmeed, Wael ; Kroh, Matthew ; Sahebkar, Amirhossein |
Link: | |
Zeitschrift: | Obesity Surgery, Jg. 34 (2024-05-01), Heft 5, S. 1929-1937 |
Veröffentlichung: | 2024 |
Medientyp: | academicJournal |
ISSN: | 0960-8923 (print) |
DOI: | 10.1007/s11695-024-07210-8 |
Schlagwort: |
|
Sonstiges: |
|