Reports from Masaryk Memorial Cancer Institute Advance Knowledge in Cancer (Dual Detection System for Cancer-associated Point Mutations Assisted By a Multiplexed Lna-based Amperometric Bioplatform Coupled With Rolling Circle Amplification).

A recent study conducted at the Masaryk Memorial Cancer Institute in Brno, Czech Republic, has developed a novel electrochemical bioplatform for the analysis of a specific DNA point mutation in the BRAF proto-oncogene, known as V600E. This mutation is considered an important biomarker in various types of cancer. The bioplatform utilizes rolling circle amplification and locked nucleic acid capture probes to detect the mutation, and it does not require PCR or sophisticated instrumentation. The study represents a significant advancement in the field of cancer research and has been peer-reviewed. [Extracted from the article]

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