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Nonsteroidal Anti-inflammatory Therapy and Recurrent Acute Anterior Uveitis.
In: Ocular Immunology & Inflammation, Jg. 18 (2010-04-01), Heft 2, S. 116-120
Online
academicJournal
Zugriff:
Objective: To investigate oral nonsteroidal anti-inflammatory drug (NSAID) therapy in the prevention of recurrences of uveitis in patients with recurrent nongranulomatous, idiopathic, or HLA-B27-associated acute anterior uveitis (AAU). Methods: Retrospective case series of 59 patients with recurrent AAU treated with celecoxib or diflunisal. Results: The average duration of NSAID therapy was 21.2 ± 5.7 months. The average number of relapses for all patients prior to systemic NSAID therapy was 2.84 per person-year follow-up. These relapses declined to 0.53 per person-year follow-up with NSAID therapy ( p < .001). The relapse rates prior to and after treatment in the HLA-B27-positive group ( n = 21) were compared with the relapse rates prior to and after treatment in the HLA-B27-negative group ( n = 38) and were also statistically significant ( p < .001). Conclusion: Morbid attacks and the cumulative exposure to corticosteroids can be prevented with systemic NSAID therapy in patients with recurrent AAU. [ABSTRACT FROM AUTHOR]
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Titel: |
Nonsteroidal Anti-inflammatory Therapy and Recurrent Acute Anterior Uveitis.
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Autor/in / Beteiligte Person: | Fiorelli, Vanessa M. B. ; Bhat, Pooja ; Stephen Foster, C. |
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Zeitschrift: | Ocular Immunology & Inflammation, Jg. 18 (2010-04-01), Heft 2, S. 116-120 |
Veröffentlichung: | 2010 |
Medientyp: | academicJournal |
ISSN: | 0927-3948 (print) |
DOI: | 10.3109/09273941003587558 |
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