Adult-Onset Still's Disease Complicated by Immunoglobulin A Vasculitis and anti-CCP Antibody-Positive Arthritis.
In: Tohoku Journal of Experimental Medicine, Jg. 255 (2021-12-01), Heft 4, S. 297-301
Online
academicJournal
Zugriff:
A 38-year-old male was admitted to our hospital for arthralgia, fever, skin rash, and purpura. He was diagnosed as having adult-onset Still's disease (AOSD) based on Yamaguchi's criteria. Skin biopsy revealed immunoglobulin A (IgA) vasculitis. He was also found to have anti-cyclic citrullinated peptide (CCP) antibody-positive inflammatory arthritis on a shoulder joint, however he did not fulfill classification criteria for rheumatoid arthritis. Elevated serum cytokine such as serum IL-18 supported the diagnosis of AOSD. His symptoms improved with 40 mg of prednisolone plus cyclosporin A (200 mg/day). Two years after hospitalization, AOSD was relapsed with pleurisy and hyperferritinemia. Finally, he was diagnosed with multicyclic systemic type of AOSD complicated by IgA vasculitis and seropositivity of anti-CCP antibody. Clinicians need to consider the complication of multiple rheumatic diseases, even if the diseasespecific autoantibody is positive [ABSTRACT FROM AUTHOR]
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Titel: |
Adult-Onset Still's Disease Complicated by Immunoglobulin A Vasculitis and anti-CCP Antibody-Positive Arthritis.
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Autor/in / Beteiligte Person: | Fujita, Yuya ; Sato, Shuzo ; Matsumoto, Haruki ; Temmoku, Jumpei ; Yashiro-Furuya, Makiko ; Matsuoka, Naoki ; Asano, Tomoyuki ; Yokose, Kohei ; Yoshida, Shuhei ; Ohtsuka, Mikio ; Watanabe, Hiroshi ; Migita, Kiyoshi |
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Zeitschrift: | Tohoku Journal of Experimental Medicine, Jg. 255 (2021-12-01), Heft 4, S. 297-301 |
Veröffentlichung: | 2021 |
Medientyp: | academicJournal |
ISSN: | 0040-8727 (print) |
DOI: | 10.1620/tjem.255.297 |
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