Findings from Royan Institute for Stem Cell Biology and Technology Broaden Understanding of Nanocarriers (Shell-sheddable and Charge Switchable Magnetic Nanoparticle As Ph-sensitive Nanocarrier for Targeted Drug Delivery Applications).
In: Drug Week, 2024-05-03, S. 327-327
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Zugriff:
A study conducted by the Royan Institute for Stem Cell Biology and Technology in Tehran, Iran, has developed a pH-sensitive magnetic nanocarrier for targeted drug delivery. The nanocarrier was prepared using Fe3O4@SiO2 nanoparticles coated with polyethyleneimine (PEI) and polyethyleneglycol (PEG). The nanocarrier showed potential for delivering curcumin, an anticancer drug, to prostate cancer cells. The study found that the curcumin-loaded magnetic nanoparticles (C-LMNs) exhibited more cytotoxicity to human prostate cancer cells and induced a higher rate of late apoptotic/necrotic cells compared to pure magnetic nanoparticles. [Extracted from the article]
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Titel: |
Findings from Royan Institute for Stem Cell Biology and Technology Broaden Understanding of Nanocarriers (Shell-sheddable and Charge Switchable Magnetic Nanoparticle As Ph-sensitive Nanocarrier for Targeted Drug Delivery Applications).
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Zeitschrift: | Drug Week, 2024-05-03, S. 327-327 |
Veröffentlichung: | 2024 |
Medientyp: | serialPeriodical |
ISSN: | 1531-6440 (print) |
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