Influence of bFGF combined with degradable membrane on nerve regeneration following delayed facial nerve injury. (English)
In: China Journal of Oral & Maxillofacial Surgery, Jg. 11 (2013), Heft 1, S. 24-28
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Zugriff:
PURPOSE: To study the effect of bFGF combined with degradable membrane on nerve regeneration following delayed facial nerve injury. METHODS: Sixty SD rats were randomly divided into bFGF combined with degradable membrane group (bFGF combined with degradable membrane was implanted), degradable membrane group (the membrane without bFGF was implanted) and control group (no membrane was implanted) with 20 rats in each group. Rat models of facial nerve injury was established. Three weeks postoperatively, the breakpoint of facial nerve was dissected and anastomosed after prune nodes. After 12 weeks, the samples were selected and were observed morphologically. The number and diameter of myelinated nerve fibers as well as the velocity of action potential were measured in the three groups. The data was analyzed using SPSS 11.5 software package. RESULTS: The number and diameter of regenerated facial nerve fibers, the velocity of action potential were more, thicker, faster, respectively, as compared with the experimental group and the control group. There was significant difference between the two groups (P<0.05). There was no significant difference between the control group and the normal group (P>0.05). CONCLUSION: bFGF combined with degradable membrane can promote the regeneration of facial nerve following delayed facial nerve injury in rats. [ABSTRACT FROM AUTHOR]
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Influence of bFGF combined with degradable membrane on nerve regeneration following delayed facial nerve injury. (English)
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Autor/in / Beteiligte Person: | Qiang, WANG ; Zhu, ZHANG ; Shi-yan, ZHANG ; Xue-yan, SU ; Wen-bo, LI ; Shi-nrn, CHEN |
Zeitschrift: | China Journal of Oral & Maxillofacial Surgery, Jg. 11 (2013), Heft 1, S. 24-28 |
Veröffentlichung: | 2013 |
Medientyp: | academicJournal |
ISSN: | 1672-3244 (print) |
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