Effects of dietary protein on whole-body protein turnover and endocrine function in young-adult and aging dogs2
In: Journal of Animal Science, Jg. 79 (2001-12-01), Heft 12, S. 3128-3136
serialPeriodical
Zugriff:
Thirty-six adult female Beagles averaging 2 (young-adult) or 8 (geriatric) yr of age were used to assess the effects of graded levels of dietary protein (16, 24, or 32%) on endocrine-controlled regulation of whole-body protein turnover. Rates of whole-body protein synthesis (WBPS) and whole-body protein degradation (WBPD) were estimated using orally administered 15N-glycine and total excreta collection. Although N balance was similar for all dogs, N flux through the metabolic pool increased linearly (P< 0.05) as protein intake increased. Rates of WBPS, WBPD, or the difference between them were not influenced by age (P> 0.10). A quadratic increase (P< 0.05) in WBPS and WBPD was observed in response to dietary protein. Serum insulin-like growth factor-I (IGF-I), IGF-I-binding protein 3, and total IGF-I-binding proteins were higher (P< 0.05) in geriatric dogs than in young-adult dogs regardless of protein intake. These results indicate that dietary protein in excess of 16% may not be required to maintain N balance in young-adult and aging dogs despite the linear increase in N flux through the metabolic pool. Furthermore, age-induced changes in endocrine functionality may differ between dogs and other species.
Titel: |
Effects of dietary protein on whole-body protein turnover and endocrine function in young-adult and aging dogs2
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Autor/in / Beteiligte Person: | Williams, C. C. ; Cummins, K. A. ; Hayek, M. G. ; Davenport, G. M. |
Zeitschrift: | Journal of Animal Science, Jg. 79 (2001-12-01), Heft 12, S. 3128-3136 |
Veröffentlichung: | 2001 |
Medientyp: | serialPeriodical |
ISSN: | 0021-8812 (print) ; 1525-3163 (print) |
DOI: | 10.2527/2001.79123128x |
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