Correlations between coronary flow reserve measured with a Doppler guide wire and treadmill exercise testing
In: American Heart Journal, Jg. 134 (1997-07-01), Heft 1, S. 99-104
serialPeriodical
Zugriff:
We compared exercise test results to a physiologic depiction of stenosis severity, coronary flow reserve (CFR), measured with a Doppler guide wire in 35 patients with single-vessel coronary disease. Group 1 ( n = 21) had abnormal CFR, and group 2 ( n = 14) had normal CFR. In group 1, 14 of 21 had ST-segment depression versus 3 of 14 in group 2 ( p < 0.01). Exercise treadmill time (Bruce protocol) was normalized to the age- and sex-predicted time. Exercise time and normalized exercise time were less in group 1 (5.6 +/- 2.3 vs 9.9 +/- 1.8 min and 0.82 +/- 0.32 vs 1.25 +/- 0.23, p < 0.00001). Having either ST-segment depression or a normalized exercise time <1 during exercise had a 95% sensitivity, 71% specificity, and 86% predictive accuracy in identifying abnormal CFR. Coronary stenoses and minimal lumen diameter were similar in groups 1 and 2. By using stepwise logistical regression analysis, exercise time and ST-segment depression predicted CFR with a total r^2 of 0.51. Minimal lumen diameter did not significantly add to the model. Exercise test variables, ST-segment depression, and exercise time are predictive of the physiologic significance of coronary lesions. (Am Heart J 1997;134:99-104.)
Titel: |
Correlations between coronary flow reserve measured with a Doppler guide wire and treadmill exercise testing
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Autor/in / Beteiligte Person: | Schulman, D.S. ; Lasorda, D. ; Farah, T. ; Soukas, P. ; Reichek, N. ; Joye, J.D. |
Zeitschrift: | American Heart Journal, Jg. 134 (1997-07-01), Heft 1, S. 99-104 |
Veröffentlichung: | 1997 |
Medientyp: | serialPeriodical |
ISSN: | 0002-8703 (print) ; 1097-6744 (print) |
DOI: | 10.1016/S0002-8703(97)70112-1 |
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