Magnetic resonance imaging-based texture analysis for the prediction of postoperative clinical outcome in uterine cervical cancer
In: Abdominal Radiology, Jg. 47 (2021-10-04), S. 352-361
Online
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Zugriff:
Magnetic resonance imaging (MRI)-based texture analysis (MRTA) is a novel image analysis tool that offers objective information about the spatial arrangement of MRI signal intensity. We aimed to investigate the value of MRTA in predicting the postoperative clinical outcome of patients with uterine cervical cancer. This retrospective study included 115 patients with surgically proven cervical cancer who underwent preoperative pelvic 3T-MRI, and MRTA was performed on T2-weighted images (T2), apparent diffusion coefficient (ADC) maps, and contrast-enhanced T1-weighted images (CE-T1). Filtration histogram-based texture analysis was used to generate six first-order statistical parameters [mean intensity, standard deviation (SD), mean of positive pixels (MPP), entropy, skewness, and kurtosis] at five spatial scaling factors (SSFs, 2–6 mm) as well as from unfiltered images. Cox proportional hazard models and time-dependent receiver operating characteristic analyses were used to evaluate the associations between parameters and recurrence-free survival (RFS). During a median follow-up of 36 months, tumor recurrence was found in 26 patients (22.6%). Multivariate analysis demonstrated that CE-T1 MPP and T2 kurtosis at SSF3–5, CE-T1 MPP at SSF6, and CE-T1 SD at unfiltered images were independent predictors of RFS (p optimal cutoff values demonstrated significantly worse survival than those with ≤ optimal cutoff values (p
Titel: |
Magnetic resonance imaging-based texture analysis for the prediction of postoperative clinical outcome in uterine cervical cancer
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Autor/in / Beteiligte Person: | Chan Kyo Kim ; Ka Eun Kim |
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Zeitschrift: | Abdominal Radiology, Jg. 47 (2021-10-04), S. 352-361 |
Veröffentlichung: | Springer Science and Business Media LLC, 2021 |
Medientyp: | unknown |
ISSN: | 2366-0058 (print) ; 2366-004X (print) |
DOI: | 10.1007/s00261-021-03288-1 |
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