S14-3. F-wave and spinal excitability in neurological disease
In: Clinical Neurophysiology, Jg. 129 (2018-05-01), S. e28- (2S.)
Online
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Zugriff:
Depending on the neurological condition, the excitability of lower motoneuron (LMN) changes. Shortest latency, conduction velocity, frequency and amplitude are F-wave parameters we are able to measure. Because F-wave travels the entire length of peripheral nerve, parameters of latency and conduction velocity are used to evaluate motor neuropathies. However, frequency and amplitude are considered to reflect the excitability of LMN. Normally, LMN receives presynaptic inhibition from upper motoneuron (UMN) or Renshaw inhibitory cell. In case of central nervous system disorders like stroke and myelopathy, LMN excitability becomes higher because of disinhibition from those inhibitory neuron system, and is leading cause of F-wave frequency and amplitude increase. In diseases that lower LMN excitability such as motor neuron disease and neuropathy, F-wave frequency diminishes. Evaluation of amplitude would be somewhat complicated. Even though F-wave frequency diminishes, F-wave amplitude increases in relation to motor unit size, which is affected by reinnervation process. In amyotrophic lateral sclerosis, where both UMN and LMN progressively disappear, the balance of both neurons decides the excitability of LMN. Therefore, the frequency and amplitude of F-wave varies. Repeater F-wave might be the key to analyze this complicated condition.
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S14-3. F-wave and spinal excitability in neurological disease
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Autor/in / Beteiligte Person: | Abe, Tatsuya |
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Zeitschrift: | Clinical Neurophysiology, Jg. 129 (2018-05-01), S. e28- (2S.) |
Veröffentlichung: | Elsevier BV, 2018 |
Medientyp: | unknown |
ISSN: | 1388-2457 (print) |
DOI: | 10.1016/j.clinph.2018.02.058 |
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