CCQ and ACQ scores in obstructive lung disease: one questionnaire for all?

Introduction: Different standardized questionnaires have been developed to assess and monitor obstructive lung disease (OLD) symptoms over time, e.g. the asthma control questionnaire (ACQ) and COPD control questionnaire (CCQ). It is not always possible to distinguish between asthma and COPD, and a relevant percentage of patients have characteristics of both diseases, the asthma COPD overlap (ACO). We hypothesize a uniform questionnaire could be used in all OLD subjects regardless of specifying diagnosis. Aims and objectives: To assess the correlation between CCQ and ACQ scores in a large cohort of OLD subjects. Methods: A cohort of 356 subjects with OLD was assessed at a tertiary reference clinic. Patients completed both ACQ and CCQ at the same visit. Statics were performed using linear regression analysis in SPSS. Results: Demographics of 356 subjects (61.3% asthma, 26.1% COPD and 12.6% ACO): mean age 53.8, 55% females, 25% active smokers, FEV1 74.5%. Mean ACQ 2.23 (SD +/- 1.15) and mean CCQ 1.87 (SD +/- 1.10). A strong correlation between CCQ and ACQ was found. CCQ could be predicted from ACQ by: CCQ = 0.645*ACQ + 1.021, adjusted R2 = 0.39, p Conclusion: There is a highly significant correlation between CCQ and ACQ score in OLD. This illustrates the potential room for development of a uniform questionnaire for all OLD subjects.