ChemInform Abstract: DBU Mediated Confluent Approach for the One Pot Synthesis of Novel 5-Hydroxy Pyrazolo[1,2-a][1,2,4]triazoles and Their Dehydration to Novel Pyrazolo[1,2-a][1,2,4]triazole Derivatives
In: ChemInform, Jg. 47 (2016-10-01)
Online
unknown
Zugriff:
A series of novel alkyl 5-hydroxy-7-aryl-5-methyl-1,3-dioxo-2-phenyl hexahydropyrazolo[1,2-a][1,2,4]triazole-6-carboxylates and alkyl 5-aryl-7-methyl-1,3-dioxo-2-phenyl-1,2,3,5-tetra hydropyrazolo[1,2-a][1,2,4]triazole-6-carboxylates have been synthesized. The synthesis of hydroxy pyrazolo[1,2-a][1,2,4]triazoles has been achieved by DBU mediated one pot reaction of aromatic aldehydes, alkyl acetoacetates and 4-phenylurazole at 35 °C in ethanol–water (1:1). Dehydration of hydroxy pyrazolo[1,2-a][1,2,4]triazoles has been achieved using conc. H2SO4 to afford dehydrated pyrazolo[1,2-a][1,2,4]triazoles in high yields. The structural assignments have been made by spectral data and unambiguously confirmed by X-ray analysis. Good yields, operational simplicity and moderate conditions are the advantages of the reactions.
Titel: |
ChemInform Abstract: DBU Mediated Confluent Approach for the One Pot Synthesis of Novel 5-Hydroxy Pyrazolo[1,2-a][1,2,4]triazoles and Their Dehydration to Novel Pyrazolo[1,2-a][1,2,4]triazole Derivatives
|
---|---|
Autor/in / Beteiligte Person: | Gupta, Shruti ; Khurana, Jitender M. ; Saluja, Pooja |
Link: | |
Zeitschrift: | ChemInform, Jg. 47 (2016-10-01) |
Veröffentlichung: | Wiley, 2016 |
Medientyp: | unknown |
ISSN: | 0931-7597 (print) |
DOI: | 10.1002/chin.201643125 |
Schlagwort: |
|
Sonstiges: |
|