Experimental Use of Transcranial Magnetic Stimulation (TMS) to Treat Tinnitus in a Deaf Patient
In: Clinical Medical Reviews and Case Reports, Jg. 2 (2015-03-31)
Online
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Zugriff:
A 28-year-old deaf female patient underwent 10 sessions of repetitive Transcranial Magnetic Stimulation (rTMS) as a participant in a placebo-controlled clinical trial for treatment of tinnitus. Trial participants received 2000 pulses of rTMS per session at a stimulation rate of 1 Hz. The neural target for rTMS was auditory cortex within Heschl’s gyrus. The primary outcome measure was the Tinnitus Functional Index (TFI); secondary outcome measures included a Visual Numeric Scale (VNS) for selfrated tinnitus loudness, Beck Depression Inventory II (BDI-II) and State Anxiety Inventory (SAI). Assessments were conducted at baseline, immediately after the last (10 th ) rTMS session, and 1, 2, 4, 13 and 26 weeks after the last rTMS session. At baseline, the patient’s TFI score was 27.6, which indicates that tinnitus was not a severe problem for her. After 10 rTMS sessions, her scores on the TFI, BDI and SAI increased (worsened), while the VNS score for tinnitus loudness decreased from 5.1 at baseline to 3.5. Her TFI score remained elevated at all follow-up assessments until week 26 when this score returned to its baseline level. Approximately half of the tinnitus patients in the clinical trial who received active rTMS (18 of 35) exhibited significant reductions in TFI scores that were sustained throughout the follow-up period. The fact that this patient did not benefit from rTMS might be attributed to the following factors: Low TFI baseline score; sub-optimal TMS stimulus intensity; suboptimal neural target for TMS. Although this patient did not benefit from rTMS, additional participants with profound hearing loss + bothersome tinnitus should be tested to determine if some of them do benefit from the procedure. Because many forms of sound therapy for tinnitus management are not practical for patients with profound hearing loss, rTMS might be a potential treatment option for this population.
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Experimental Use of Transcranial Magnetic Stimulation (TMS) to Treat Tinnitus in a Deaf Patient
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Autor/in / Beteiligte Person: | Folmer, Robert L. ; Theodoroff, Sarah M. |
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Zeitschrift: | Clinical Medical Reviews and Case Reports, Jg. 2 (2015-03-31) |
Veröffentlichung: | ClinMed International Library, 2015 |
Medientyp: | unknown |
ISSN: | 2378-3656 (print) |
DOI: | 10.23937/2378-3656/1410023 |
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