ChemInform Abstract: A Palladium Catalyzed Route to a Benzofuran Analogue of Indolactam V ( ILV): Effects on PKC Isotype Selectivity
In: ChemInform, Jg. 26 (2010-08-18)
Online
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Zugriff:
A novel palladium catalyzed synthesis of the benzofuran analogue 11 of n-hexyl-ILV and details of its isoform selectivity are described. Of considerable interest is the unexpected finding that this subtle structural change leads to a compound that is more like phorbol 12,13-dibutyrate (PDBu) and less like n- octyl-ILV in its pattern of activity.
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ChemInform Abstract: A Palladium Catalyzed Route to a Benzofuran Analogue of Indolactam V ( ILV): Effects on PKC Isotype Selectivity
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Autor/in / Beteiligte Person: | Ma, Dawei ; Lewin, Nancy E. ; Du, Linh ; Blumberg, Peter M. ; Kozikowski, Alan P. |
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Zeitschrift: | ChemInform, Jg. 26 (2010-08-18) |
Veröffentlichung: | Wiley, 2010 |
Medientyp: | unknown |
ISSN: | 0931-7597 (print) |
DOI: | 10.1002/chin.199507298 |
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