Cloning and Sequence Analysis of the Spike Gene from Several Feline Coronaviruses
In: Coronaviruses ISBN: 9781461363057; (1994)
Online
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Zugriff:
The DNA sequence encoding the spike gene from the DF2 strain of Type II feline infectious peritonitis virus (FIPV), a temperature sensitive FIPV virus (TS-DF2) and an isolate of feline enteric coronavirus (FECV 1683) were determined. Comparison of the published WSU 1146 and DF2 FIPV S genes showed that the viruses shared a high degree of homology (99.6%). Likewise, the S gene of the virulent DF2 FIPV virus was closely conserved to that isolated from the vaccine virus strain, TS-DF2 FIPV. In contrast, the FECV S gene had numerous DNA and amino acid differences when compared to the virulent FIPV sequences. Sequence differences among the feline coronavirus isolates were localized to the amino-terminus region of the S gene.
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Cloning and Sequence Analysis of the Spike Gene from Several Feline Coronaviruses
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| Autor/in / Beteiligte Person: | Elaine Verne Jones ; Klepfer, Sharon ; Miller, Timothy J. ; A. Paul Reed |
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| Quelle: | Coronaviruses ISBN: 9781461363057; (1994) |
| Veröffentlichung: | Springer US, 1994 |
| Medientyp: | unknown |
| ISBN: | 978-1-4613-6305-7 (print) |
| DOI: | 10.1007/978-1-4615-2996-5_3 |
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