DBU-Catalyzed Rearrangement of Secondary Propargylic Alcohols: An Efficient and Cost-Effective Route to Chalcone Derivatives
In: Synlett, Jg. 31 (2020-07-24), S. 1587-1592
Online
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Zugriff:
A 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU)-catalyzed rearrangement of diarylated secondary propargylic alcohols to give α,β-unsaturated carbonyl compounds has been developed. The typical 1,3-transposition of oxy functionality, characteristic of Mayer–Schuster rearrangements, is not observed in this case. A broad substrate scope, functional-group tolerance, operational simplicity, complete atom economy, and excellent yields are among the prominent features of the reaction. Additionally, the photophysical properties and crystal-structure-packing behavior of selected compounds were investigated and found to be of interest.
| Titel: |
DBU-Catalyzed Rearrangement of Secondary Propargylic Alcohols: An Efficient and Cost-Effective Route to Chalcone Derivatives
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| Autor/in / Beteiligte Person: | Bera, Mrinal K. ; Savarimuthu, Antony ; Hasija, Avantika ; Chopra, Deepak ; De, Rimpa ; Ballav, Tamal ; Singh, Pijush ; Nanda, Jayanta |
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| Zeitschrift: | Synlett, Jg. 31 (2020-07-24), S. 1587-1592 |
| Veröffentlichung: | Georg Thieme Verlag KG, 2020 |
| Medientyp: | unknown |
| ISSN: | 1437-2096 (print) ; 0936-5214 (print) |
| DOI: | 10.1055/s-0040-1707909 |
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