Modulation of Wound Repair by Members of the Fibroblast Growth Factor Family
In: The Molecular and Cellular Biology of Wound Repair ISBN: 9781489901873; (1988)
Online
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Zugriff:
The fibroblast growth factors (FGFs) comprise a family of at least nine structurally homologous polypeptides that are found in a variety of cells and tissues (Baird and Bohlen, 1990; Brem and Klagsbrun, 1993; Burgess and Maciag, 1989; Folkman and Klagsbrun, 1987; Klagsbrun, 1989; Klagsbrun and D’Amore, 1991; Klagsbrun and Folkman, 1990; Rifkin and Moscatelli, 1989; Tanaka et al., 1992; Miyamoto et al., 1993). This family includes acidic FGF (aFGF), basic FGF (bFGF), int-2 protein, HST/K-FGF, FGF-5, FGF-6, keratinocyte growth factor (KGF), androgen-induced growth factor (AIGF), and glia-activating factor (GAF) (see Table I). These growth factors have been enumerated as FGF-1 through FGF-9, respectively, in order to simplify the nomenclature (Baird and Klagsbrun, 1991). However, since the name KGF is still widely used, the designation “KGF/FGF-7” will be used here in referring to this factor. The aFGF (FGF-1) and bFGF (FGF-2) proteins are the most extensively characterized FGF family members in terms of detailed knowledge concerning structure and biological activity.
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Modulation of Wound Repair by Members of the Fibroblast Growth Factor Family
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| Autor/in / Beteiligte Person: | Klagsbrun, Michael ; Abraham, Judith A. |
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| Quelle: | The Molecular and Cellular Biology of Wound Repair ISBN: 9781489901873; (1988) |
| Veröffentlichung: | Springer US, 1988 |
| Medientyp: | unknown |
| ISBN: | 978-1-4899-0187-3 (print) |
| DOI: | 10.1007/978-1-4899-0185-9_6 |
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