An improved synthesis of pyrroles fromN-p-toluenesulfonylglycine esters and α,β-unsaturated aldehydes and ketones
In: Journal of Heterocyclic Chemistry, Jg. 28 (1991-11-01), S. 1671-1676
Online
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Zugriff:
N-p-Toluenesulfonylglycine esters 2 condensed with α,β-unsaturated carbonyl compounds 1 in the presence of the non-nucleophilic base DBU to give hydroxypyrrolidines 3. Dehydration with phosphorus oxychloride-pyridine, followed by DBU mediated elimination of p-toluenesulfinic acid, gave a series of synthetically useful pyrrole-2-carboxylates 5.
Titel: |
An improved synthesis of pyrroles fromN-p-toluenesulfonylglycine esters and α,β-unsaturated aldehydes and ketones
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Autor/in / Beteiligte Person: | Lash, Timothy D. ; Hoehner, Michael C. |
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Zeitschrift: | Journal of Heterocyclic Chemistry, Jg. 28 (1991-11-01), S. 1671-1676 |
Veröffentlichung: | Wiley, 1991 |
Medientyp: | unknown |
ISSN: | 1943-5193 (print) ; 0022-152X (print) |
DOI: | 10.1002/jhet.5570280705 |
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