Choice of hydrogen bonds or halogen bonds by 2-halogenated 5-morpholinomethylphenyl triazolo[1,5-a]pyridine
In: CrystEngComm, Jg. 20 (2018), S. 3006-3010
Online
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Zugriff:
The crystal structures of halogenated 1,2,4-triazolo[1,5-a]pyridine derivatives disclose intriguing structural chemistry features dictated by the formation of either hydrogen bonds (HBs) or halogen bonds (XBs). 2-Chloride and bromide derivatives (1 and 2) favor HBs, promoting the formation of bent-shaped conformers. The 2-iodide compound (3) favors XBs, leading to different shaped conformers split into polymorphic forms. The XB-mediated crystals (3I and 3II) are more thermodynamically stable than the HB-mediated crystals of 1 and 2.
| Titel: |
Choice of hydrogen bonds or halogen bonds by 2-halogenated 5-morpholinomethylphenyl triazolo[1,5-a]pyridine
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| Autor/in / Beteiligte Person: | Weimin, Li ; Yingying, Chai ; Zhen, Shen ; Ma, Beibei ; Changfu, Li ; Ridong, Huang ; He, Yang ; Bojiang, Chen ; Zhou, Xinglong ; Hai, Chen |
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| Zeitschrift: | CrystEngComm, Jg. 20 (2018), S. 3006-3010 |
| Veröffentlichung: | Royal Society of Chemistry (RSC), 2018 |
| Medientyp: | unknown |
| ISSN: | 1466-8033 (print) |
| DOI: | 10.1039/c8ce00423d |
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