SIX-YEAR FOLLOWUP OF NEONATAL RENOVASCULAR (NRH) HYPERTENSION
In: Pediatric Research, Jg. 18 (1984-04-01), S. 357A
Online
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Zugriff:
Neonatal hypertension is often associated with renal artery thrombosis after use of umbilical artery catheters. Although infants with NRH usually respond to medical therapy, their prognosis is unclear; longterm followup of 11 infants is presented. Mean birthweight was 2914 gm; pre-treatment blood pressure, 161/100 mmHg, and age of onset, 7.8 days. 9 of 11 infants had umbilical artery catheters. A renal abnormality was noted on renal scan or angiography in 9 of 11 infants. 7 of 10 infants studied had elevated peripheral plasma renin activity (PRA). All infants became normotensive with diuretic and/or antihypertensive agents and remained so when weaned off drugs. 2 infants died at 3 months of age of SIDS and pneumonia. The remaining have been followed for 5.5 to 7.5 years. 2 children, neither small for gestational age, have heights and weights below the 5th percentile for age. One child has a creatinine clearance of 62 ml/min/1.73 m2. PRA in 8 children studied is normal. Renal ultrasound, intravenous pyelography, and renal scan demonstrate persistent renal abnormalities in 7 of 9 children. Neonates with NRH responded well to antihypertensive medication, remained normotensive off medications, but had significant abnormalities in renal size and function which persisted over a 6 year period. Because their ultimate prognosis is unclear, longterm followup of infants with NRH is indicated.
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SIX-YEAR FOLLOWUP OF NEONATAL RENOVASCULAR (NRH) HYPERTENSION
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Autor/in / Beteiligte Person: | Adelman, Raymond D. |
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Zeitschrift: | Pediatric Research, Jg. 18 (1984-04-01), S. 357A |
Veröffentlichung: | Springer Science and Business Media LLC, 1984 |
Medientyp: | unknown |
ISSN: | 1530-0447 (print) ; 0031-3998 (print) |
DOI: | 10.1203/00006450-198404001-01585 |
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