Approaching different stages of the disease and the correlated treatment on Molar Incisor Hypomineralization (MIH): a systematic review and meta-analysis

Review question / Objective: This systematic review aims to define and evaluate the treatments available for two different stages of the Molar Incisor Hypomineralization (MIH) defect. On stage I, the lesion is classified as Mild and is characterized by demarcated opacities without posteruptive breakdown. On stage II, the lesion is classified as Severe and is characterized by posteruptive breakdown of enamel. To this end, the proposed study will answer the following question: What are the treatments available and their results for the two different stages of MIH on permanent teeth? Condition being studied: Mild and Severe Molar Incisor Hypomineralization (MIH). MIH is an enamel defect that occurs during the mineralization on the second stage of the formation of the enamel called maturation phase. This disease affects the outer layer of enamel, making the structure soft and undercalcified. The appearance of the lesion can be white opaque to yellow brown depending on the stage ( mild or severe).