Changes in the Lipid Peroxidation—Antioxidant Protection System in Women with Ovarian Hyperandrogenism at Different Periods of Reproductive Age
In: Bulletin of Experimental Biology and Medicine, Jg. 170 (2021), S. 308-311
Online
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Zugriff:
We studied changes in LPO processes and antioxidant protection system in women with ovarian hyperandrogenism at various periods of reproductive age 18-45 years. An age-related decrease in total antioxidant activity and accumulation of secondary LPO products, ketodiens and coupled trienes, were found; these changes were accompanied by an increase in the level of superoxide dismutase and a decrease in the concentrations of reduced glutathione, α-tocopherol, and retinol. Women of early reproductive age (18-35 years) with hyperandrogenism were characterized by increased content of oxidized glutathione accompanied by a decrease in the level of α-tocopherol and retinol in comparison with the control group. In women of late reproductive age (35-45 years) with hyperandrogenism, increased superoxide dismutase activity in comparison with the control group was revealed.
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Changes in the Lipid Peroxidation—Antioxidant Protection System in Women with Ovarian Hyperandrogenism at Different Periods of Reproductive Age
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Autor/in / Beteiligte Person: | Krusko, O. V. ; Kolesnikov, Sergey I. ; Grebenkina, Lyudmila ; Belenkaya, L. V. ; Sholokhov, L. F. ; Kurashova, N. A. ; Kolesnikova, Lyubov |
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Zeitschrift: | Bulletin of Experimental Biology and Medicine, Jg. 170 (2021), S. 308-311 |
Veröffentlichung: | Springer Science and Business Media LLC, 2021 |
Medientyp: | unknown |
ISSN: | 1573-8221 (print) ; 0007-4888 (print) |
DOI: | 10.1007/s10517-021-05057-y |
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