Adult lactose intolerance, calcium intake, bone metabolism and bone density in German-Turkish immigrants
In: Journal of Bone and Mineral Metabolism, Jg. 38 (2019-12-04), S. 378-384
Online
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Zugriff:
Adult lactose intolerance (ALI) significantly alters calcium intake and absorption, and thus may promote osteoporosis. ALI is a recessive condition with a geographical north–south gradient characterised by decreased levels of intestinal lactase. PCR-based genotyping of lactase (LCT) gene polymorphisms is a safe and easy way to diagnose ALI and may complement diagnostic procedures to identify individuals at risk for reduced calcium intake and subsequently osteoporosis due to lactose malabsorption. Therefore, we investigated the frequency of ALI and its influence on calcium intake, markers of bone metabolism and bone mineral density (BMD) in a cohort of Turkish immigrants living in Germany. We investigated single nucleotide polymorphisms of the LCT gene, calcium intake, markers of bone metabolism and BMD in 183 Turkish immigrants. ALI was diagnosed in 154 out of 183 (81%) probands. ALI was significantly associated with self-reported lactose intolerance (p
Titel: |
Adult lactose intolerance, calcium intake, bone metabolism and bone density in German-Turkish immigrants
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Autor/in / Beteiligte Person: | Lange, Uwe ; Klemm, Philipp ; Dischereit, Gabriel |
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Zeitschrift: | Journal of Bone and Mineral Metabolism, Jg. 38 (2019-12-04), S. 378-384 |
Veröffentlichung: | Springer Science and Business Media LLC, 2019 |
Medientyp: | unknown |
ISSN: | 1435-5604 (print) ; 0914-8779 (print) |
DOI: | 10.1007/s00774-019-01070-4 |
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