Genetic evidence for the existence of two quinone related inhibitor binding sites in NADH-CoQ reductase
In: Biochimica et Biophysica Acta (BBA) - Bioenergetics, Jg. 1319 (1997-03-01), S. 1-4
Online
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Zugriff:
Using the NADH-CoQ reductase of Rhodobacter capsulatus as a model for the mitochondrial Complex I, we have for the first time isolated bacterial mutants resistant to piericidin-A, a classical inhibitor of the mitochondrial enzyme. Their sensitivity to other inhibitors directed towards the quinone binding domain of complex I gives direct genetic evidence for the existence of two inhibitor binding sites.© 1977 Elsevier Science B.V. All rights reserved.
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Genetic evidence for the existence of two quinone related inhibitor binding sites in NADH-CoQ reductase
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Autor/in / Beteiligte Person: | Darrouzet, Elisabeth ; Dupuis, Alain |
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Zeitschrift: | Biochimica et Biophysica Acta (BBA) - Bioenergetics, Jg. 1319 (1997-03-01), S. 1-4 |
Veröffentlichung: | Elsevier BV, 1997 |
Medientyp: | unknown |
ISSN: | 0005-2728 (print) |
DOI: | 10.1016/s0005-2728(97)00009-1 |
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