Chinese herbal medicine reduces mortality in patients with severe and critical Coronavirus disease 2019: a retrospective cohort study
In: Frontiers of medicine, Jg. 14 (2020-04-14), Heft 6
Online
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Zugriff:
This study aimed to evaluate the efficacy of Chinese herbal medicine (CHM) in patients with severe/critical coronavirus disease 2019 (COVID-19). In this retrospective study, data were collected from 662 patients with severe/critical COVID-19 who were admitted to a designated hospital to treat patients with severe COVID-19 in Wuhan before March 20, 2020. All patients were divided into an exposed group (CHM users) and a control group (non-users). After propensity score matching in a 1:1 ratio, 156 CHM users were matched by propensity score to 156 non-users. No significant differences in seven baseline clinical variables were found between the two groups of patients. All-cause mortality was reported in 13 CHM users who died and 36 non-users who died. After multivariate adjustment, the mortality risk of CHM users was reduced by 82.2% (odds ratio 0.178, 95% CI 0.076–0.418; P < 0.001) compared with the non-users. Secondly, age (odds ratio 1.053, 95% CI 1.023–1.084; P < 0.001) and the proportion of severe/critical patients (odds ratio 0.063, 95% CI 0.028–0.143; P < 0.001) were the risk factors of mortality. These results show that the use of CHM may reduce the mortality of patients with severe/critical COVID-19.
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Chinese herbal medicine reduces mortality in patients with severe and critical Coronavirus disease 2019: a retrospective cohort study
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Autor/in / Beteiligte Person: | Qiao, Jie ; Ke, Yuhe ; Lang, Suping ; Wei, Li ; Luo, Dan ; Xia, Ping ; Fan, An ; Yang, Shuo ; Jia, Wen ; Meng, Qing-Bin ; Zheng, Yujiao ; Chen, Guohua ; Su, Wen ; Tong, Xiaolin ; Wang, Chuan ; Yang, Jia-Yao ; Lian, Fengmei ; Li, Xiuyang ; Zhang, Ying ; Fan, Xuepeng |
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Zeitschrift: | Frontiers of medicine, Jg. 14 (2020-04-14), Heft 6 |
Veröffentlichung: | 2020 |
Medientyp: | unknown |
ISSN: | 2095-0225 (print) |
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