External validation of the PROGRESS-CTO perforation risk score
In: Catheterization and Cardiovascular Interventions, Jg. 101 (2023-02-01), Heft 2, S. 326-332
Online
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Zugriff:
Background: Coronary artery perforation is one of the most feared and common complications of chronic total occlusion (CTO) percutaneous coronary intervention (PCI). Methods: To assess the usefulness of the recently developed PROGRESS-CTO (NCT02061436) perforation risk score in independent cohorts. Individual patient-level data pooled analysis of three registries was performed. Results: Of the 4566 patients who underwent CTO PCI at 25 centers, 196 (4.2%) had coronary artery perforation. Patients with perforations were older (69 ± 10 vs. 65 ± 10, p < 0.001), more likely to be women (19% vs. 13%, p = 0.009), more likely to have a history of prior coronary artery bypass graft (34% vs. 20%, p < 0.001), and unfavorable angiographic characteristics such as blunt stump (62% vs. 48%, p < 0.001), proximal cap ambiguity (52% vs. 34%, p < 0.001), and moderate-severe calcification (60% vs. 49%, p = 0.002). Technical success was lower in patients with perforations (73% vs. 88%, p < 0.001). The area under the receiver operating characteristic curve of the PROGRESS-CTO perforation risk model was 0.76 (95% confidence interval [CI], 0.72−0.79), with good calibration (Hosmer-Lemeshow p = 0.97). We found that the CTO PCI perforation risk increased with higher PROGRESS-CTO perforation scores: 0.3% (score 0), 2.3% (score 1), 3.1% (score 2), 5.5% (score 3), 7.5% (score 4), 14.6% (score 5). Conclusion: Given the good discriminative performance, calibration, and the ease of calculation, the PROGRESS-CTO perforation score may facilitate assessment of the risk of perforation in patients undergoing CTO PCI.
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External validation of the PROGRESS-CTO perforation risk score
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Autor/in / Beteiligte Person: | Simsek, Bahadir ; Tajti, Peter ; Carlino, Mauro ; Ojeda, Soledad ; Pan, Manuel ; Rinfret, Stephane ; Vemmou, Evangelia ; Kostantinis, Spyridon ; Nikolakopoulos, Ilias ; Karacsonyi, Judit ; Rempakos, Athanasios ; Dens, Joseph A. ; Agostoni, Pierfrancesco ; Alaswad, Khaldoon ; Megaly, Michael ; Avran, Alexandre ; Choi, James W. ; Jaffer, Farouc A. ; Doshi, Darshan ; Karmpaliotis, Dimitri ; Khatri, Jaikirshan J. ; Knaapen, Paul ; Alessio La Manna ; Spratt, James C. ; Tanabe, Masaki ; Walsh, Simon ; Mastrodemos, Olga C. ; Allana, Salman ; Rangan, Bavana V. ; Goktekin, Omer ; Gorgulu, Sevket ; Poommipanit, Paul ; Kearney, Kathleen E. ; Lombardi, William L. ; J. Aaron Grantham ; Mashayekhi, Kambis ; Brilakis, Emmanouil S. ; Azzalini, Lorenzo ; Cardiology ; ACS - Atherosclerosis & ischemic syndromes ; Fakültesi, Tıp |
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Zeitschrift: | Catheterization and Cardiovascular Interventions, Jg. 101 (2023-02-01), Heft 2, S. 326-332 |
Veröffentlichung: | 2023 |
Medientyp: | unknown |
ISSN: | 1522-1946 (print) |
DOI: | 10.1002/ccd.30551 |
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