Cytomegalovirus cultures during maintenance DHPG therapy for cytomegalovirus (CMV) retinitis in acquired immunodeficiency syndrome (AIDS)
In: Journal of Medical Virology, Jg. 30 (1990), S. 42-44
Online
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Zugriff:
Nine patients with acquired immunodeficiency syndrome (AIDS) and cytomegalovirus (CMV) retinitis on maintenance therapy with ganciclovir: 9(1,3-dihydroxy-2-propoxymethyl) guanine (DHPG) at high dose (30 mg/kg/week) or low dose (20 mg/kg/week) were tested every 1-2 weeks for CMV isolation from blood, saliva, and urine. Duration of therapy ranged from 1.5 to 12 months (average 5.3 months). During pretreatment and low-dose and high-dose maintenance therapy, CMV was isolated from 48/59 (81%), 90/211 (43%), and 40/290 (14%) of specimens, respectively. Three patients with progressive retinitis had viraemia more frequently than did six patients with stable retinitis, CMV being isolated from 29/47 (62%) and 17/121 (14%) of blood samples, respectively.
| Titel: |
Cytomegalovirus cultures during maintenance DHPG therapy for cytomegalovirus (CMV) retinitis in acquired immunodeficiency syndrome (AIDS)
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| Autor/in / Beteiligte Person: | Cr, Lucas ; Hayes, K ; Maclean, H ; I D Jennens ; Am, Sandland |
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| Zeitschrift: | Journal of Medical Virology, Jg. 30 (1990), S. 42-44 |
| Veröffentlichung: | Wiley, 1990 |
| Medientyp: | unknown |
| ISSN: | 1096-9071 (print) ; 0146-6615 (print) |
| DOI: | 10.1002/jmv.1890300109 |
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