Effects of beta-CCE on retention of aversively- and appetitively-motivated tasks in rats
In: Physiologybehavior, Jg. 60 (1996-10-01), Heft 4
Online
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Zugriff:
Beta-carboline-3-carboxylic acid ethyl ester (beta-CCE; 1.0 or 5.0 mg/kg, i.p.) or vehicle control was administered to male Sprague-Dawley rats immediately after training in an aversively- or appetitively-motivated task. Aversively-motivated training consisted of a one-trial step-though inhibitory (passive) avoidance task with a 0.6 mA, 1.0 s foot shock. Retention was tested 21 days after training. The 5.0 mg/kg dose of beta-CCE significantly enhanced retention performance in the inhibitory avoidance task compared to the vehicle control. For appetitive training, the animals learned a T-maze for water reward. Retention was tested 48 h later, and neither dose of beta-CCE was found to affect retention performance. These results suggest that beta-CCE, when administered immediately after training, may alter retention performance of an aversively-motivated task but not an appetitive task.
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Effects of beta-CCE on retention of aversively- and appetitively-motivated tasks in rats
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Autor/in / Beteiligte Person: | Jensen, Robert A. ; Wichlinski, Lawrence J. |
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Zeitschrift: | Physiologybehavior, Jg. 60 (1996-10-01), Heft 4 |
Veröffentlichung: | 1996 |
Medientyp: | unknown |
ISSN: | 0031-9384 (print) |
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