Measuring the coding potential of genomic sequences through a combination of triplet occurrence patterns and RNY preference
In: Journal of molecular evolution, Jg. 59 (2004-11-24), Heft 3
Online
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Zugriff:
The distribution of n-tuplet frequencies is shown to strongly correlate with functionality when examining a genomic sequence in a reading-frame specific manner. The approach described herein applies a coarse-graining procedure, which is able to reveal aspects of triplet usage that are related to protein coding, while at the same time remaining species independent, based on a simple summation of suitable triplet occurrences measures. These quantities are ratios of simple frequencies to suitable mononucleotide-frequency products promoting the incidence of the RNY motif, preferred in the most widely used codons. A significant distinction of coding and noncoding sequences is achieved.
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Measuring the coding potential of genomic sequences through a combination of triplet occurrence patterns and RNY preference
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Autor/in / Beteiligte Person: | Almirantis, Yannis ; Nikolaou, Christoforos |
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Zeitschrift: | Journal of molecular evolution, Jg. 59 (2004-11-24), Heft 3 |
Veröffentlichung: | 2004 |
Medientyp: | unknown |
ISSN: | 0022-2844 (print) |
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