Association of cardiometabolic health factors with age-related executive function and episodic memory
In: Aging, Neuropsychology, and Cognition, Jg. 29 (2021-05-02), S. 746-760
Online
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Zugriff:
Although decline of cognitive abilities in late life is regarded as a common facet of aging, there is inter-individual variability in this decline. Possible contributors are cardiometabolic risk factors associated with cerebrovascular dysfunction, but a dearth in unifying health-cognition models confound exactly how these risk factors mediate age-related changes in executive function (EF) and episodic memory. This study investigated the indirect effect of age on these cognitive abilities via cardiometabolic risk factors using a structural equation modeling approach. Participants included 738 adults (64% female) ranging from 21 to 85 years of age (M = 47.47, SD = 18.28). An exploratory factor analysis was applied to an EF battery yielding a two-factor solution, consisting of inhibition and cognitive flexibility, that showed acceptable fit (χ(2)(48) = 101.84, p < .001, CFI = .980, RMSEA = .039, SRMR = .035). The EF latent factors were then included in a confirmatory factor analysis exploring the indirect role of age on episodic memory and EF via blood pressure, cholesterol, triglycerides and body mass index. The theoretical model demonstrated acceptable fit, χ(2)(108) = 204.071, p < .001, CFI = .972, RMSEA = .035, SRMR = .035. Blood pressure was associated with lower cognitive flexibility (β = −.20, p < .001) and there was a significant indirect effect of age on episodic memory through cognitive flexibility (β = .07, p = .021). Results support the “Executive Decline Hypothesis” of age-related episodic memory decline and specifically implicate lower blood pressure control and cognitive flexibility in these changes.
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Association of cardiometabolic health factors with age-related executive function and episodic memory
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Autor/in / Beteiligte Person: | McIntosh, Roger C. ; Lobo, Judith D. ; Goodman, Zachary T. ; Uddin, Lucina Q. ; Schmaus, Jennifer A. |
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Zeitschrift: | Aging, Neuropsychology, and Cognition, Jg. 29 (2021-05-02), S. 746-760 |
Veröffentlichung: | Informa UK Limited, 2021 |
Medientyp: | unknown |
ISSN: | 1744-4128 (print) ; 1382-5585 (print) |
DOI: | 10.1080/13825585.2021.1915948 |
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