Effects of Xuezhitong in Patients with Hypertriglyceridemia: a Multicentre, Randomized, Double-Blind, Double Simulation, Positive Drug and Placebo Parallel Control Study
In: Cardiovascular drugs and therapy, Jg. 34 (2020-03-25), Heft 4
Online
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Zugriff:
Backgroud Xuezhitong (XZT) is an extract of Allium macrostemon Bunge that has lipid-lowering properties. Objective To evaluate the effects of XZT on lipids in subjects with hypertriglyceridemia (HTG) without severe dyslipidaemia. Methods A total of 358 subjects with HTG were enrolled and randomly assigned to receive XZT (2700 mg daily), xuezhikang (XZK) (1200 mg daily) or placebo. The primary endpoint was the reduction or percent reduction in the TG level over 12 weeks of treatment. Results At the 12-week follow-up, a reduction in the TG level from baseline was observed in both groups, but the XZT and XZK groups demonstrated a significantly greater reduction than the placebo group (30.77%, 24.02% vs 11.59%, P P P Conclusions XZT significantly reduced TG levels and was well tolerated. Longer-term studies in more diverse patient populations are needed to corroborate these findings. Clinical Trial Registration www.chictr.org.cn Identifier: ChiCTR1900025854.
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Effects of Xuezhitong in Patients with Hypertriglyceridemia: a Multicentre, Randomized, Double-Blind, Double Simulation, Positive Drug and Placebo Parallel Control Study
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Autor/in / Beteiligte Person: | Liu, Jing ; Li, Lei ; Li, Dong ; Lin, Qian ; Wan, Jie ; Lu, Jin-Jin ; Ding, Junpin ; Cui, Xiaoyun ; Jia, Wenhao ; Zou, Ting ; Li, Yan |
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Zeitschrift: | Cardiovascular drugs and therapy, Jg. 34 (2020-03-25), Heft 4 |
Veröffentlichung: | 2020 |
Medientyp: | unknown |
ISSN: | 1573-7241 (print) |
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