Repeated cross-sectional analysis of hydroxychloroquine deimplementation in the AHA COVID-19 CVD Registry
In: Scientific Reports Scientific Reports, Jg. 11 (2021), Heft 1, S. 1-4
Online
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Zugriff:
There is little data describing trends in the use of hydroxychloroquine for COVID-19 following publication of randomized trials that failed to demonstrate a benefit of this therapy. We identified 13,957 patients admitted for active COVID-19 at 85 U.S. hospitals participating in a national registry between March 1 and August 31, 2020. The overall proportion of patients receiving hydroxychloroquine peaked at 55.2% in March and April and decreased to 4.8% in May and June and 0.8% in July and August. At the hospital-level, median use was 59.4% in March and April (IQR 48.5–71.5%, range 0–100%) and decreased to 0.3% (IQR 0–5.4%, range 0–100%) by May and June and 0% (IQR 0–1.3%, range 0–36.4%) by July and August. The rate and hospital-level uniformity in deimplementation of this ineffective therapy for COVID-19 reflects a rapid response to evolving clinical information and further study may offer strategies to inform deimplementation of ineffective clinical care.
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Repeated cross-sectional analysis of hydroxychloroquine deimplementation in the AHA COVID-19 CVD Registry
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Autor/in / Beteiligte Person: | R. Kannan Mutharasan ; Wang, Tracy Y. ; Roth, Gregory A. ; Gupta, Divya ; Rodriguez, Fatima ; Gluckman, Ty J. ; Sandeep R Das ; Bradley, Steven M. ; Shah, Rashmee U. ; Khera, Rohan ; Peterson, Pamela N. ; Emmons-Bell, Sophia |
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Zeitschrift: | Scientific Reports Scientific Reports, Jg. 11 (2021), Heft 1, S. 1-4 |
Veröffentlichung: | Nature Publishing Group UK, 2021 |
Medientyp: | unknown |
ISSN: | 2045-2322 (print) |
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