Parameters for Contrast-Enhanced Ultrasound (CEUS) of Enlarged Superficial Lymph Nodes for the Evaluation of Therapeutic Response in Lymphoma: A Preliminary Study
In: Medical Science Monitor, Jg. 23 (2017-11-15), S. 5430-5438
Online
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Zugriff:
BACKGROUND The aims of this preliminary study were to evaluate contrast-enhanced ultrasound (CEUS) imaging and the therapeutic response of enlarged superficial lymph nodes in patients with lymphoma before and after chemotherapy and to determine the most useful CEUS response parameters. MATERIAL AND METHODS Forty-three patients with lymphoma, with 43 enlarged superficial lymph nodes, underwent CEUS and conventional ultrasound (US), before treatment and after the first three cycles of chemotherapy. Clinical responses included overall response (OR) and no response (NR). Imaging parameters by time-intensity curve (TIC) included basic intensity (B), wash-out slope and/or decent slope (K), wash-in slope or rise slope (C), time to peak (TTP), area under the gamma curve (Area), arrive time(ATM), peak intensity (PI), change of peak intensity (I) were compared. And receiver operating characteristic (ROC) curve analysis was operated. RESULTS Quantitative parameters of CEUS before and after the first three cycles of chemotherapy showed a significant difference in the AreaΔ, PID, and IΔ in the OR group compared with NR group (P
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Parameters for Contrast-Enhanced Ultrasound (CEUS) of Enlarged Superficial Lymph Nodes for the Evaluation of Therapeutic Response in Lymphoma: A Preliminary Study
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Autor/in / Beteiligte Person: | Ding, Zhaoyan ; Xin, Lei ; Zhao, Cheng ; Yan, Zhimei ; Zhang, Xiaojuan ; Zang, Yichen ; Xue, Hongwei |
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Zeitschrift: | Medical Science Monitor, Jg. 23 (2017-11-15), S. 5430-5438 |
Veröffentlichung: | International Scientific Information, Inc., 2017 |
Medientyp: | unknown |
ISSN: | 1643-3750 (print) |
DOI: | 10.12659/msm.907293 |
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