Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events

Fowkes, FGR ; Murray, GD ; et al.

In: Fowkes, F G R, Murray, G D, Butcher, I, Folsom, A R, Hirsch, A T, Couper, D J, deBacker, G, Kornitzer, M, Newman, A B, Sutton-Tyrrell, K C, Cushman, M, Lee, A J, Price, J F, D'Agostino, R B, Murabito, J M, Norman, P E, Masaki, K H, Bouter, L M, Heine, R J, Stehouwer, C D A, McDermott, M M, Stoffers, H E J H, Knottnerus, J A, Ogren, M, Hedblad, B, Koenig, W, Meisinger, C, Cauley, J A, Franco, O H, Hunink, M G M, Hofman, A, Witteman, J C, Criqui, M H, Langer, R D, Hiatt, W R & Hamman, R F 2014, ' Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events ', European Journal of Preventive Cardiology, vol. 21, no. 3, pp. 310-320 https://doi.org/10.1177/2047487313516564 Fowkes, F G R, Murray, G D, Butcher, I, Folsom, A R, Hirsch, A T, Couper, D J, deBacker, G, Kornitzer, M, Newman, A B, Sutton-Tyrrell, K C, Cushman, M, Lee, A J, Price, J F, D'Agostino, R B, Murabito, J M, Norman, P E, Masaki, K H, Bouter, L M, Heine, R J, Stehouwer, C D A, McDermott, M M, Stoffers, H E J H, Knottnerus, J A, Ogren, M, Hedblad, B, Koenig, W, Meisinger, C, Cauley, J A, Franco, O H, Hunink, M G M, Hofman, A, Witteman, J C, Criqui, M H, Langer, R D, Hiatt, W R & Hamman, R F 2014, ' Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events ', European journal of preventive cardiology, vol. 21, no. 3, pp. 310-320 . https://doi.org/10.1177/2047487313516564 European journal of preventive cardiology, 21(3), 310-320. SAGE Publications Ltd European journal of preventive cardiology, vol 21, iss 3 European Journal of Preventive Cardiology, 21(3), 310-320. SAGE Publications Ltd

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BackgroundThe ankle brachial index (ABI) is related to risk of cardiovascular events independent of the Framingham risk score (FRS). The aim of this study was to develop and evaluate a risk model for cardiovascular events incorporating the ABI and FRS.DesignAn analysis of participant data from 18 cohorts in which 24,375 men and 20,377 women free of coronary heart disease had ABI measured and were followed up for events.MethodsSubjects were divided into a development and internal validation dataset and an external validation dataset. Two models, comprising FRS and FRS + ABI, were fitted for the primary outcome of major coronary events.ResultsIn predicting events in the external validation dataset, C-index for the FRS was 0.672 (95% CI 0.599 to 0.737) in men and 0.578 (95% CI 0.492 to 0.661) in women. The FRS + ABI led to a small increase in C-index in men to 0.685 (95% CI 0.612 to 0.749) and large increase in women to 0.690 (95% CI 0.605 to 0.764) with net reclassification improvement (NRI) of 4.3% (95% CI 0.0 to 7.6%, p = 0.050) and 9.6% (95% CI 6.1 to 16.4%, p

Titel:	Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events
Autor/in / Beteiligte Person:	Fowkes, FGR ; Murray, GD ; Butcher, I ; Folsom, AR ; Hirsch, AT ; Couper, DJ ; Debacker, G ; Kornitzer, M ; Newman, AB ; Sutton-Tyrrell, KC ; Cushman, M ; Lee, AJ ; Price, JF ; D'Agostino, RB ; Murabito, JM ; Norman, Pe ; Masaki, KH ; Bouter, LM ; Heine, RJ ; Stehouwer, CDA ; McDermott, MM ; Stoffers, HEJH ; Knottnerus, JA ; Ogren, M ; Hedblad, B ; Koenig, W ; Meisinger, C ; Cauley, JA ; Franco, Oh ; Hunink, MGM ; Hofman, A ; Witteman, JC ; Criqui, MH ; Langer, RD ; Hiatt, WR ; Hamman, RF ; Ankle Brachial Index Collaboration ; EMGO+ - Lifestyle, Overweight and Diabetes ; Epidemiology and Data Science ; medicine, Internal ; EMGO - Lifestyle, overweight and diabetes ; Geneeskunde, Interne ; Medicine, Family ; RS: CAPHRI School for Public Health and Primary Care ; RS: CARIM - R3 - Vascular biology ; RS: CAPHRI - Implementation of Evidence ; RS: CAPHRI - Diagnosis and treatment of frequently occuring diseases in general practice ; RS: CAPHRI - Clinical epidemiology ; RS: CAPHRI - Asthma and, COPD ; Epidemiology ; Radiology & Nuclear Medicine
Link:	View record in OpenAIRE (Volltext) https://research.vumc.nl/en/publications/bbc8bdb6-b02f-4087-9edb-db932eb7450f
Quelle:	Fowkes, F G R, Murray, G D, Butcher, I, Folsom, A R, Hirsch, A T, Couper, D J, deBacker, G, Kornitzer, M, Newman, A B, Sutton-Tyrrell, K C, Cushman, M, Lee, A J, Price, J F, D'Agostino, R B, Murabito, J M, Norman, P E, Masaki, K H, Bouter, L M, Heine, R J, Stehouwer, C D A, McDermott, M M, Stoffers, H E J H, Knottnerus, J A, Ogren, M, Hedblad, B, Koenig, W, Meisinger, C, Cauley, J A, Franco, O H, Hunink, M G M, Hofman, A, Witteman, J C, Criqui, M H, Langer, R D, Hiatt, W R & Hamman, R F 2014, ' Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events ', European Journal of Preventive Cardiology, vol. 21, no. 3, pp. 310-320 https://doi.org/10.1177/2047487313516564 Fowkes, F G R, Murray, G D, Butcher, I, Folsom, A R, Hirsch, A T, Couper, D J, deBacker, G, Kornitzer, M, Newman, A B, Sutton-Tyrrell, K C, Cushman, M, Lee, A J, Price, J F, D'Agostino, R B, Murabito, J M, Norman, P E, Masaki, K H, Bouter, L M, Heine, R J, Stehouwer, C D A, McDermott, M M, Stoffers, H E J H, Knottnerus, J A, Ogren, M, Hedblad, B, Koenig, W, Meisinger, C, Cauley, J A, Franco, O H, Hunink, M G M, Hofman, A, Witteman, J C, Criqui, M H, Langer, R D, Hiatt, W R & Hamman, R F 2014, ' Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events ', European journal of preventive cardiology, vol. 21, no. 3, pp. 310-320 . https://doi.org/10.1177/2047487313516564 European journal of preventive cardiology, 21(3), 310-320. SAGE Publications Ltd European journal of preventive cardiology, vol 21, iss 3 European Journal of Preventive Cardiology, 21(3), 310-320. SAGE Publications Ltd
Veröffentlichung:	2014
Medientyp:	unknown
ISSN:	2047-4873 (print)
Schlagwort:	Male Time Factors Epidemiology Cardiorespiratory Medicine and Haematology Cardiovascular Risk model Models Risk Factors 80 and over Medicine LOWER-EXTREMITY Young adult Aged, 80 and over Framingham Risk Score PRIMARY-CARE Statistical Middle Aged Prognosis Europe medicine.anatomical_structure Heart Disease PRACTICE GUIDELINES Cardiovascular Diseases Predictive value of tests Female Cardiology and Cardiovascular Medicine Risk assessment Adult medicine.medical_specialty animal structures Clinical Sciences ALL-CAUSE Risk Assessment Article White People Young Adult Sex Factors SDG 3 - Good Health and Well-being Clinical Research Predictive Value of Tests Humans CORONARY-HEART-DISEASE Ankle Brachial Index cardiovascular diseases OLDER-ADULTS Aged Models, Statistical business.industry PERIPHERAL ARTERIAL-DISEASE Prevention Reproducibility of Results Coronary heart disease United States body regions Cardiovascular System & Hematology Ankle Brachial Index Collaboration Physical therapy PRESSURE INDEX Ankle FOLLOW-UP business TASK-FORCE
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