GLUCOSE-TRANSPORT IN HUMAN SKELETAL-MUSCLE - THE INVIVO RESPONSE TO INSULIN
In: Scopus-Elsevier; (1993)
Online
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Zugriff:
Transmembrane glucose transport plays a key role in determining insulin sensitivity. We have measured in vivo WBGU, FGU, and KIn and Kout of 3-O-methyl-D-glucose in forearm skeletal muscle by combining the euglycemic clamp technique, the forearm-balance technique, and a novel dual-tracer (1-[3H]-L-glucose and 3-O-[4C]-methyl-D-glucose) technique for measuring in vivo transmembrane transport. Twenty-seven healthy, lean subjects were studied. During saline infusion, insulin concentration, FGU (n = 6), KIn, and Kout (n = 4) were similar to baseline. During SRIF-induced hypoinsulinemia (insulin
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GLUCOSE-TRANSPORT IN HUMAN SKELETAL-MUSCLE - THE INVIVO RESPONSE TO INSULIN
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Autor/in / Beteiligte Person: | Saccomani, Mp ; DeFronzo, R. A. ; Zych, Ks ; Bonadonna, R. ; Cobelli, C. ; Ferrannini, Eleuterio ; Seely, L |
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Quelle: | Scopus-Elsevier; (1993) |
Veröffentlichung: | 1993 |
Medientyp: | unknown |
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