Assessment of synergistic combination potential of probiotic and bacteriophage against antibiotic-resistant Staphylococcus aureus exposed to simulated intestinal conditions
In: Archives of Microbiology, Jg. 196 (2014-07-12), S. 719-727
Online
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Zugriff:
This study was designed to evaluate the combined effect of probiotic Lactobacillus rhamnosus and bacteriophage SA11 on the control of antibiotic-sensitive Staphylococcus aureus (ASSA) and antibiotic-resistant S. aureus (ARSA) under the simulated intestinal conditions. The survivability of ASSA and ARSA were determined in the simulated phosphate-buffered saline (PBS)-, trypticase soy broth (TSB)-, and milk-based gastric juices adjusted to pH 2.0, 3.0, and 5.0 at 37 °C for 30 min. The inhibitory effect of bacteriophage SA11 and probiotic on the growth of ASSA and ARSA was evaluated in the simulated intestinal juices at 37 °C for 20 h. The least reductions in the numbers of ASSA and ARSA were observed in the milk-based gastric juices at pH 2.0 (
| Titel: |
Assessment of synergistic combination potential of probiotic and bacteriophage against antibiotic-resistant Staphylococcus aureus exposed to simulated intestinal conditions
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| Autor/in / Beteiligte Person: | Woo, Jihoon ; Ahn, Juhee |
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| Zeitschrift: | Archives of Microbiology, Jg. 196 (2014-07-12), S. 719-727 |
| Veröffentlichung: | Springer Science and Business Media LLC, 2014 |
| Medientyp: | unknown |
| ISSN: | 1432-072X (print) ; 0302-8933 (print) |
| DOI: | 10.1007/s00203-014-1013-z |
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