Light exposure at night is associated with subclinical carotid atherosclerosis in the general elderly population: the HEIJO-KYO cohort
In: Chronobiology international, Jg. 32 (2014-10-31), Heft 3
Online
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Zugriff:
Epidemiological and cellular biological studies indicate the influence of impaired circadian biological rhythmicity on atherosclerosis. Increased exposure to light at night (LAN) is common in modern life, and LAN exposure is the most important environmental cue for circadian misalignment. However, the association between LAN exposure and atherosclerosis has never been explored in humans. In this cross-sectional study, we measured nighttime light intensity in the bedroom along with the intima-media thickness (IMT) of the common carotid artery using ultrasonography in 700 elderly individuals (mean age 71.6 years). Averages of mean and maximal carotid IMT were 0.88 ± 0.15 mm and 1.09 ± 0.32 mm, respectively. Median intensity of LAN exposure was 0.74 lux (interquartile range, 0.08-3.34). Both mean and maximal carotid IMT significantly increased across quartiles of increasing LAN intensity (p for trend = 0.002 and
Titel: |
Light exposure at night is associated with subclinical carotid atherosclerosis in the general elderly population: the HEIJO-KYO cohort
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Autor/in / Beteiligte Person: | Saeki, Keigo ; Obayashi, Kenji ; Kurumatani, Norio |
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Zeitschrift: | Chronobiology international, Jg. 32 (2014-10-31), Heft 3 |
Veröffentlichung: | 2014 |
Medientyp: | unknown |
ISSN: | 1525-6073 (print) |
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