Impact of type 2 diabetes on manifestations and treatment outcome of pulmonary tuberculosis
In: Epidemiology and Infection, Jg. 137 (2008-06-18), S. 203-210
Online
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Zugriff:
SUMMARYDiabetes mellitus (DM) is a known risk factor for pulmonary tuberculosis (PTB). This study aimed to determine if type 2 DM alters manifestations and treatment outcome of PTB. Records of 217 consecutive culture-proven PTB patients were analysed retrospectively. The manifestations and treatment outcomes of 74 patients with type 2 DM (PTB-DM group) were compared to 143 patients without DM (PTB group). PTB-DM patients showed higher frequencies of fever, haemoptysis, positive acid-fast bacilli sputum smears, and consolidation, cavity, and lower lung field lesions on chest radiographs, and higher mortality rate. Furthermore, type 2 DM, age ⩾65 years, and extensive radiographic disease were factors independently associated with an unfavorable outcome. This study confirmed that clinical manifestations and chest radiographs of PTB patients associated with type 2 DM significantly depart from the typical presentation. Type 2 DM seems to have a negative effect on treatment outcome of PTB.
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Impact of type 2 diabetes on manifestations and treatment outcome of pulmonary tuberculosis
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Autor/in / Beteiligte Person: | Chen, Huang-Chi ; Huang, Ming-Shyang ; Yang, Chih-Jen ; Hwang, Jhi-Jhu ; Wang, Chao-Chuan ; Chuang, Shih-Chang ; Chong, Inn-Wen |
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Zeitschrift: | Epidemiology and Infection, Jg. 137 (2008-06-18), S. 203-210 |
Veröffentlichung: | Cambridge University Press (CUP), 2008 |
Medientyp: | unknown |
ISSN: | 1469-4409 (print) ; 0950-2688 (print) |
DOI: | 10.1017/s0950268808000782 |
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