Feeding mode influences dynamic gut microbiota signatures and affects susceptibility to anti-CD3 mAb-induced intestinal injury in neonatal mice
In: American journal of physiology. Gastrointestinal and liver physiology, Jg. 323 (2023-09-01), Heft 3
Online
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Zugriff:
Feeding modes influence the gut microbiome, immune system, and intestinal barrier homeostasis in neonates; how feeding modes impact susceptibility to neonatal gastrointestinal (GI) diseases is still uncertain. Here, we investigated the impact of dam feeding (DF) and formula feeding (FF) on features of the gut microbiome and physiological inflammation during the first 2 days of postnatal development and on the susceptibility to intestinal injury related to the inflammatory state in neonatal mouse pups. 16S rRNA sequencing data revealed microbiome changes, lower α-diversity, and a distinct pattern of β-diversity including expansion of
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Feeding mode influences dynamic gut microbiota signatures and affects susceptibility to anti-CD3 mAb-induced intestinal injury in neonatal mice
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Autor/in / Beteiligte Person: | Subramanian, Saravanan ; Geng, Hua ; Du, Chao ; Chou, Pauline M. ; Bu, Heng-Fu ; Wang, Xiao ; Swaminathan, Suchitra ; Tan, Stephanie C. ; Ridlon, Jason M. ; Isabelle G. De Plaen ; Tan, Xiao-Di |
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Zeitschrift: | American journal of physiology. Gastrointestinal and liver physiology, Jg. 323 (2023-09-01), Heft 3 |
Veröffentlichung: | 2023 |
Medientyp: | unknown |
ISSN: | 1522-1547 (print) |
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