Incidence of vein thrombosis in peripheral intravenous nutrition: effect of fat emulsions
In: Clinical nutrition (Edinburgh, Scotland), Jg. 18 (1999-08-25), Heft 2
Online
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Zugriff:
The relative risk of thrombophlebitis induced by either Long-chain Triglycerides (LCTs) or Medium-chain Triglycerides (MCTs) during peripheral i.v. nutrition (PIN) was evaluated. A total of 76 patients were randomly assigned into group A (n=40) and group B (n=36). The nutritional requirements in both groups were covered by a standardized regime of osmolality 1130 mOsm and pH 5.2, which provided 14 kg/day(-1) nitrogen, 600 kcal/day(-1) of carbohydrates and 1000 kcal/day(-1) of lipids. Group A received the lipids as pure LCTs while group B received a mixture of LCTs/MCTs at a ratio 1:1. The infused nutritional volume was 2000 ml and was delivered via a suitable vein in a proximal forearm, using a fine bore polyurethane 22G catheter. The two standardized regimes were evaluated over a 10 day period regarding the incidence of thrombophlebitis. The cumulative risk of thrombophlebitis was documented to be significantly lower in group A compared to group B (17.5% versus 44.4%, P < 0.05). LCTs appear to prolong peripheral vein feeding by lessening the reaction of venous endothelium to the irritating nutritional infusate.
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Incidence of vein thrombosis in peripheral intravenous nutrition: effect of fat emulsions
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Autor/in / Beteiligte Person: | Papadimitriou, J. ; Smirniotis, V. ; Kotsis, Thomas ; Kourias, E. ; Labrou, A. ; Kostopanagiotou, Georgia ; Antoniou, S. |
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Zeitschrift: | Clinical nutrition (Edinburgh, Scotland), Jg. 18 (1999-08-25), Heft 2 |
Veröffentlichung: | 1999 |
Medientyp: | unknown |
ISSN: | 0261-5614 (print) |
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