The Utility of N-Terminal Pro-Brain Natriuretic Peptide as an Adjunct Diagnostic Tool for Acute Heart Failure in Acute Dyspneic Patients Coming to the Emergency Department: A Retrospective Review of Our Early Experience
In: Malaysian Journal of Medical Sciences, Jg. 28 (2021-08-26), S. 146-152
Online
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Zugriff:
Acute dyspnea is one of the prevalent reasons for admission to the emergency department. The use of N-terminal pro-B-type natriuretic peptide (NT-proBNP) as an adjunct for assessing acute dyspnea is not a common practice in many public hospitals in Malaysia. This retrospective review is part of our clinical audit to determine the utility of NT-proBNP as an adjunct to non- standardised clinical evaluation in identifying acute heart failure (HF) in patients with persistent dyspnea (24 h) post-admission. In this cohort of 30 patients with acute dyspnea, NT-proBNP was positive in 20 patients (87%) with acute HF. Three patients (13%) who were treated for septic shock recorded a NT-proBNP false-positive. NT-proBNP demonstrated an overall sensitivity of 90%, a specificity of 70%, a positive predictive value of 85.7% and a negative predictive value of 77.8% in identifying acute HF. These results reinforce that age-stratified NT-proBNP cut-off values are useful for ruling-in or -out acute HF. Thus, NT-proBNP should be considered a crucial point of care, testing to decifer the conundrum of acute dyspneic patients.
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The Utility of N-Terminal Pro-Brain Natriuretic Peptide as an Adjunct Diagnostic Tool for Acute Heart Failure in Acute Dyspneic Patients Coming to the Emergency Department: A Retrospective Review of Our Early Experience
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Autor/in / Beteiligte Person: | Rajah, Rathika ; Kuan Yee Lim ; Boon Hau Ng ; Chun Ian Soo |
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Zeitschrift: | Malaysian Journal of Medical Sciences, Jg. 28 (2021-08-26), S. 146-152 |
Veröffentlichung: | Penerbit Universiti Sains Malaysia, 2021 |
Medientyp: | unknown |
ISSN: | 2180-4303 (print) ; 1394-195X (print) |
DOI: | 10.21315/mjms2021.28.4.15 |
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