Oxidative Stress as a Mechanisms of Reduced Glucose Absorption under Conditions of Immobilization Stress
In: Bulletin of Experimental Biology and Medicine, Jg. 164 (2017-11-27), S. 132-135
Online
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Zugriff:
Experimental studies demonstrated inhibition of glucose absorption in the jejunum in acute and chronic 1-h daily immobilization stress, with the maximum inhibition on day 7 of immobilization. These changes correlate with the development of oxidative stress in animals over the entire duration of the experiment, which manifested by an increase in the content of the primary and end LPO products and decrease of the total antioxidant activity of the blood. Correction of these shifts with the antioxidant drug inhibits accumulation of LPO products and increases antioxidant defense and glucose absorption rate. These data prove the important role of peroxidation in regulation of glucose absorption.
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Oxidative Stress as a Mechanisms of Reduced Glucose Absorption under Conditions of Immobilization Stress
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Autor/in / Beteiligte Person: | Darenskaya, M. A. ; Kolesnikova, L. I. ; Kolesnikova, L. R. ; Kolesnikov, Sergey I. ; Grebenkina, Lyudmila ; Suslikova, Maria ; Korytov, L. I. |
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Zeitschrift: | Bulletin of Experimental Biology and Medicine, Jg. 164 (2017-11-27), S. 132-135 |
Veröffentlichung: | Springer Science and Business Media LLC, 2017 |
Medientyp: | unknown |
ISSN: | 1573-8221 (print) ; 0007-4888 (print) |
DOI: | 10.1007/s10517-017-3941-5 |
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