Carbapenem-resistant Klebsiella pneumoniae in Barbados: Driving change in practice at the national level
In: PLoS ONE, Jg. 12 (2017), Heft 5
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Zugriff:
Introduction Carbapenem-resistant Klebsiella pneumoniae (CRKP) is of growing concern globally. The risk for transmission of antimicrobial resistant organisms across several continents to the Caribbean is a real one given its tourism industry. After a cluster of cases of CRKP were detected, several studies detailed in this report were initiated to better characterize the problem. Methods A hospital-wide point prevalence study and active surveillance were performed at Queen Elizabeth Hospital (QEH) in Barbados in 2013 to assess the prevalence of CRKP infection/colonization. Following this, a 1-year longitudinal study measured the prevalence of CRKP isolates in the hospital and across all healthcare facilities in the country. Results In 2013, eleven viable isolates of CRKP from cluster of cases were sent for molecular epidemiology studies. When sequenced, they were found to be the ST-258 clone. Identification of a cluster of cases of CRKP ST-258/512 clones indicated person-to-person transmission. In September 2013, the hospital-wide point prevalence study revealed 18% of patients (53/299) at the hospital were either colonized or infected with CRKP. The infection to colonization ratio was 1:7. Patients who were infected/colonized vs. non-colonized were older (64.7 vs. 48.7 years, p
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Carbapenem-resistant Klebsiella pneumoniae in Barbados: Driving change in practice at the national level
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Autor/in / Beteiligte Person: | Corey A Forde ; Ramon-Pardo, Pilar ; Thais dos Santos ; Singh, Nalini ; Stierman, Bryan |
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Zeitschrift: | PLoS ONE, Jg. 12 (2017), Heft 5 |
Veröffentlichung: | Public Library of Science (PLoS), 2017 |
Medientyp: | unknown |
ISSN: | 1932-6203 (print) |
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