Mutations in Long Terminal Repeats κB Transcription Factor Binding Sites in Plasma Virus Among South African People Living with HIV-1
In: AIDS research and human retroviruses, Jg. 35 (2019-02-23), Heft 6
Online
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Zugriff:
HIV-1 subtype C (HIV-1C) is responsible for the majority of infections in sub-Saharan Africa. We selected 63 plasma-derived samples and generated long terminal repeats (LTRs) amplicons from people living with HIV in South Africa to identify transcription factor binding sites. NF-κB plays an important role in regulating the viral gene expression from the viral promoter and controlling viral latency. LTR amplicons were sequenced and phylogenetically analyzed. In our data set, we identified F-κB sites (
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Mutations in Long Terminal Repeats κB Transcription Factor Binding Sites in Plasma Virus Among South African People Living with HIV-1
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Autor/in / Beteiligte Person: | Adetayo Emmanuel Obasa ; Graeme Brendon Jacobs ; Ashokkumar, Manickam ; Neogi, Ujjwal |
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Zeitschrift: | AIDS research and human retroviruses, Jg. 35 (2019-02-23), Heft 6 |
Veröffentlichung: | 2019 |
Medientyp: | unknown |
ISSN: | 1931-8405 (print) |
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