Efficient Microwave Assisted Syntheses of 2,5-Diketopiperazines in Aqueous Media †
In: Molecules Molecules, Jg. 14 (2009), Heft 8, S. 2836-2849
Online
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Zugriff:
Aqueous in situ one-pot N-Boc-deprotection-cyclization of N alpha-Boc-dipeptidyl-tert-butyl and methyl esters under microwave irradiation afforded 2,5-diketopiperazines (DKPs) in excellent yields. This protocol is rapid, safe, environmentally friendly, and highly efficient, and showed that the tert-butoxy moiety is also an excellent leaving group for these cyclizations.
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Efficient Microwave Assisted Syntheses of 2,5-Diketopiperazines in Aqueous Media †
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Autor/in / Beteiligte Person: | Escalante, Jaime ; Olivo, Horacio F. ; María Yolanda Rios ; Pérez-Picaso, Lemuel |
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Zeitschrift: | Molecules Molecules, Jg. 14 (2009), Heft 8, S. 2836-2849 |
Veröffentlichung: | Molecular Diversity Preservation International, 2009 |
Medientyp: | unknown |
ISSN: | 1420-3049 (print) |
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