Experimental and clinical evaluation of BMP2-CPC graft versus deproteinized bovine bone graft for guided bone regeneration: A pilot study
In: Dental materials journal, Jg. 40 (2020-10-09), Heft 1
Online
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Zugriff:
In this study, we proposed BMP2-incorporated calcium phosphate cement (BMP2-CPC), for application in guided bone regeneration (GBR) and compared the experimental bone restoration performance and clinical alveolar bone reconstruction outcome of BMP2-CPC with those of deproteinized bovine bone (DBB). The animal study indicated that, compared to DBB, which induced the slow ingrowth of new bone, BMP2-CPC induced numerous small growth centers for bone regeneration and facilitated a significant amount of bone regeneration in rabbit calvarial bone defects. Fewer residual graft particles remained in the BMP2-CPC-treated defects than in the DBB-treated defects. The clinical study indicated that BMP2-CPC was similar to DBB in remedying alveolar bone insufficiency and maintaining implant stability. In conclusion, the results of this present study indicate that compared to DBB, BMP2-CPC can significantly enhance in vivo bone regeneration and remodeling in rabbit calvarial bone defects and shows preliminary support on its clinical application in GBR surgeries.
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Experimental and clinical evaluation of BMP2-CPC graft versus deproteinized bovine bone graft for guided bone regeneration: A pilot study
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Autor/in / Beteiligte Person: | Si, Jiawen ; Zhi, Yin ; Steve Gf Shen ; Shen, Hongzhou ; Shi, Jun ; Zhu, Fangxing |
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Zeitschrift: | Dental materials journal, Jg. 40 (2020-10-09), Heft 1 |
Veröffentlichung: | 2020 |
Medientyp: | unknown |
ISSN: | 1881-1361 (print) |
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