Value of serum collagen triple helix repeat containing-1(CTHRC1) and 14-3-3η protein compared to anti-CCP antibodies and anti-MCV antibodies in the diagnosis of rheumatoid arthritis
In: British Journal of Biomedical Science, Jg. 78 (2020-09-07), S. 67-71
Online
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INTRODUCTION Serological markers are important in the diagnosis of rheumatoid arthritis (RA) and other connective tissues diseases This study explored the clinical value of collagen triple helix repeat containing-1 (CTHRC1) and 14-3-3η protein, compared to routine markers, in the diagnosis of RA. METHODS We recruited 103 RA patients, 105 non-RA patients (osteoarthritis, ankylosing spondylitis, systemic lupus erythematosus) and 59 healthy controls. CTHRC1, 14-3-3η, anti-cyclic citrullinated peptide antibody (anti-CCP), anti-mutated citrullinated vimentin antibody (anti-MCV), rheumatoid factor and erythrocyte sedimentation rate (ESR) levels were measured, and their diagnostic value for RA evaluated and compared. RESULTS All laboratory indices were elevated in RA (P
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Value of serum collagen triple helix repeat containing-1(CTHRC1) and 14-3-3η protein compared to anti-CCP antibodies and anti-MCV antibodies in the diagnosis of rheumatoid arthritis
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| Autor/in / Beteiligte Person: | Tan, Licheng ; Zhang, Xuan ; Liu, Y ; Dai, W ; Yu, Jianlin ; Li, J ; Huang, Jiayi ; Xiang, Y ; Song, L ; Pei, Z ; Wu, Yang ; Hu, T |
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| Zeitschrift: | British Journal of Biomedical Science, Jg. 78 (2020-09-07), S. 67-71 |
| Veröffentlichung: | Frontiers Media SA, 2020 |
| Medientyp: | unknown |
| ISSN: | 0967-4845 (print) |
| DOI: | 10.1080/09674845.2020.1810400 |
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