Characterization of microvascularization of liver tumor lesions with high resolution linear ultrasound and contrast enhanced ultrasound (CEUS) during surgery: First results
In: Clinical Hemorheology and Microcirculation, Jg. 46 (2010), S. 89-99
Online
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Zugriff:
Aim: Evaluation of high resolution linear ultrasound and intra-operative linear contrast enhanced ultrasound (CEUS) and its benefit for the detection and characterization of tumor lesions. Material and methods: Twenty patients were investigated preoperatively regarding tumor detection using CT (n = 8) or MRI (n = 12) and image fusion (VNav) (n = 3). All patients had surgery for their hepatic tumor (hepatocellular carcinoma (HCC), cholangiocellular carcinoma (CCC), metastasis, and adenoma). Ultrasound was performed intra-operatively first with B-scan using a convex probe. Than multifrequency linear transmitters (6-9 MHz, 6-15 MHz, LOGIQ E9, GE) were applied for B-scan, coulor coded Doppler sonography (CCDS) and Power Doppler followed by dynamic CEUS with Contrast Harmonic Imaging (CHI) after bolus injection of a maximum of 15 mL Sono Vue ® . Results: In 9 cases with the use of intra-operative CEUS additional tumor lesions (diameter 4—15 mm) could be detected and were histologically confirmed after surgical resection (7 cases) or intra-operative biopsy (2 cases). Using intraoperative CEUS 64 tumor lesions could be detected compared to 51 tumor lesions detected by preoperative CT or MRI (p < 0.05). Using the 6-15 MHz multifrequency linear transducer with CHI, arterial perfusion of adenomas, neuroendocrine metastases and HCC lesions was detectable. In 3 cases a resection was not achievable. Two of these cases were treated with radio frequency ablation (RFA). The other case had no curable option due to multifocal tumor manifestation. Conclusion: The intra-operative use of high-resolution linear transducer techniques with CEUS offers new diagnostic perspectives for an effective liver surgery.
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Characterization of microvascularization of liver tumor lesions with high resolution linear ultrasound and contrast enhanced ultrasound (CEUS) during surgery: First results
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Autor/in / Beteiligte Person: | P von Breitenbuch ; Feuerbach, S. ; Schreyer, Andreas G. ; C J Ross ; Rennert, Janine ; Schnitzbauer, Andreas A. ; Lamby, P. ; Menzel, C ; Scherer, Marcus N. ; Farkas, Stefan ; Jung, E.M. ; Schlitt, HJ ; Loss, M. ; Piso, Pompiliu |
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Zeitschrift: | Clinical Hemorheology and Microcirculation, Jg. 46 (2010), S. 89-99 |
Veröffentlichung: | IOS Press, 2010 |
Medientyp: | unknown |
ISSN: | 1386-0291 (print) |
DOI: | 10.3233/ch-2010-1336 |
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