Mutations in the Bordetella pertussis bvgS gene that confer altered expression of the fhaB gene in Escherichia coli
In: Journal of Bacteriology Journal of Bacteriology, American Society for Microbiology, 1994, 176 (16), pp.5163-5166 Europe PubMed Central; (1994)
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Zugriff:
The bvg locus of Bordetella pertussis, required for coordinate regulation of virulence genes in response to environmental signals, encodes two proteins, BvgS and BvgA, that belong to the bacterial two-component signal transduction systems. We have isolated spontaneous mutations of the bvg locus in Escherichia coli and analyzed their effects on the expression of fhaB::lacZY transcriptional fusions. The mutations, localized in the linker and transmitter domain of BvgS, result in increased activation of fhaB and/or in insensitivity to a modulating agent, nicotinic acid.
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Mutations in the Bordetella pertussis bvgS gene that confer altered expression of the fhaB gene in Escherichia coli
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| Autor/in / Beteiligte Person: | Ullmann, Agnes ; Goyard, Sophie ; Bellalou, Jacques ; Mireau, Hakim ; ProdInra, Migration ; Unité de recherche Génétique et amélioration des plantes (GAP) ; Institut National de la Recherche Agronomique (INRA) |
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| Quelle: | Journal of Bacteriology Journal of Bacteriology, American Society for Microbiology, 1994, 176 (16), pp.5163-5166 Europe PubMed Central; (1994) |
| Veröffentlichung: | HAL CCSD, 1994 |
| Medientyp: | unknown |
| ISSN: | 0021-9193 (print) ; 1098-5530 (print) |
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