Short- and long-term follow-up of glomerular and tubular renal markers of kidney function in hyperthyroid cats after treatment with radioiodine
In: Domestic Animal Endocrinology Domestic Animal Endocrinology, Elsevier, 2009, 36 (1), pp.45-56. ⟨10.1016/j.domaniend.2008.10.001⟩; (2009)
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Zugriff:
Hyperthyroidism can mask co-existing chronic kidney disease (CKD). Previous studies showed that post-treatment renal azotemia can be predicted by pre-treatment assessment of glomerular filtration rate (GFR). We hypothesized that treatment of hyperthyroidism may have different effects on glomerular and tubular function and these changes might be predicted by additional pre-treatment variables than GFR. Serum total T4 (TT4), creatinine and blood urea nitrogen (BUN), blood pressure (BP), body weight (BW), GFR, urine specific gravity (USG), urinary protein/creatinine ratio (UPC) and retinol binding protein/creatinine ratio (uRBP/c) were evaluated before and 1, 4, 12 and 24 weeks post-treatment with radioiodine ((131)I) in 21 non-azotemic hyperthyroid cats. Cats were divided 24 weeks post-treatment into group A (normal kidney function, n=16) and group B (impaired kidney function, n=5). Serum TT4, GFR, UPC and uRBP/c decreased significantly after treatment for the complete group and group A (P
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Short- and long-term follow-up of glomerular and tubular renal markers of kidney function in hyperthyroid cats after treatment with radioiodine
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| Autor/in / Beteiligte Person: | I van Hoek ; Daminet, Sylvie ; Vandermeulen, Eva ; Croubels, Siska ; Peremans, Kathelijne ; Kooistra, Hans S. ; Binst, Dominique ; Meyer, Evelyne ; Lefebvre, Hervé P. ; Saunders, Jimmy ; Inconnu |
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| Quelle: | Domestic Animal Endocrinology Domestic Animal Endocrinology, Elsevier, 2009, 36 (1), pp.45-56. ⟨10.1016/j.domaniend.2008.10.001⟩; (2009) |
| Veröffentlichung: | HAL CCSD, 2009 |
| Medientyp: | unknown |
| ISSN: | 0739-7240 (print) |
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